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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2494f34801de5fd3084fc0b3af0344bfad7dbdcd82e7a126122e44d07595156c' 
  AND token = 'qSuYH+hzf4HTTGG7l50oGukBSovlM91vMWH15Hmimho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}