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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c17e7741512dd303ad54b3c51ffd40dffcd26f3c244cdaa50555bde27615d827' 
  AND token = 'E1Rsppmlmh+2AedkzetGWN4yIH+4OQZVwp8zhQ6wyyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}