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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c192b0a7098513f3503b1c13a4f3f11011d463fc4be1ce3fb6b7b4af96938d3' 
  AND token = 'Y5ZzH/f1jeMmMxohTmJzJGFdnNEXCpJ1xKmT2OE/HHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}