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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48005e90a6795dd8f9c5705da0a24747281dfdd3123dec3391993e0fa718df2e' 
  AND token = 'TjWVDyAxJeNnkiyUV9YjLKL9QdA7w7/nSlghEKzxJcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}