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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2af4c23754a5e8680ac11628a21bd079ec4525bb7576e0cd4e93d6d1e6f7b1' 
  AND token = 'c/ymNYI0r3vsWyDJqeCxeZgbbXTBb6ZdvTIwj3kRGGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}