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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2470dc758c5621389a105f0f6435e826e9b177672265a2cfe8410731069a1d' 
  AND token = 'P1KlQI9/JxoaSuMCfdAPSNwda53fDItn/5NlhaYq7uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}