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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0f38c87f45c5b1ef695e23ce7059b662dbc365efe40863588097872a95d88b' 
  AND token = '2pxxmYuz/XQrV1g+y6MjPkSE3P4XZm528pqsmQ7dIZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}