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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441b292e6f866ac4aeeb3f717611fd5b1b5c5d43c5c8a90cb42b5b46b12cc874' 
  AND token = 'IyI5HpoSo3Js2VdzGimtgAm24BhnZ01XFDd6hav1xAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}