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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df24a5be42669840eda0489f5c729b443512c8f1ffc086d2ec059dfdb8a0741' 
  AND token = 'd45tKNGOg3Zc192Jcv3kLxZ0r2TUQNOe12NtZXVAnic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}