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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2ad8c45c5018eaa155132395335f484c3c9aac914632bfef612a23e8e808b6' 
  AND token = '950qnDlSSiMW6OWkv46BMl00H91FfND9pHJJQu5kpXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}