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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33baa8d2548e5e399d390efcacb5ebe6b027637bd24059a566b89688c14897cc' 
  AND token = 'IGG3Zvp/3e6Q1TwFEJCuUPq7sMP30dQq4JdsBxo7+Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}