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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051d806f9e79f0d1ea9f9b0d9002bb2491085bf19e8f2edf9e49384381290029' 
  AND token = 'OjQ4+S9MYT6PYt3Ch5Kr5DTWC+ia90VZVZ437Jt3MBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}