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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c78ff6cff26a313ce0370b56885a6de8c2000b99dc309dc7ff95ffe8d3c007' 
  AND token = 'oOWOtGpJC0OSyPwi5ib1t2tWO1OsyJ47KjXpofA3wsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}