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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ae2ecc6dbb1ff6021509113702eefe64562f30cdb89207222e5f6b67e77c807' 
  AND token = 'WB3aQtgyG6fQ0jOO4DQQjFuAdUzrJlXw5JOJFjMl7d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}