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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3893f852a18ca8a15e188234323043a3f4f812e0871748c88febf6d3fdcb44dc' 
  AND token = 'hS447e9g+LcusVn9NVujV9mMMF3RDIaShdbLiTVSjrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}