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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e852bb2d4c106d7a2ec3f34aaa45bad16cae2e5b6a3b6117c1cf5ca11433225d' 
  AND token = 'XNsi69WUix8QRd8NdzuIryCvd116ClyqYdwUT6TudCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}