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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c360f5375d0d752846348db785772b4b2b643b66fc38b5b4a175228f9f197cad' 
  AND token = 'NrurN8tyioTK64adTsAUyfzPObLFkROIAH8PNCN//aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}