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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462d95b0588e6c5a45ebd29c3b59fc1188c975527cfecc7dd68915d30158f3d4' 
  AND token = '8Vu0QBLioJRfU2SUwSX/9dTAMUKsTXWR90BkOhzt9Ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}