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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb3e54eca5c1c2a29dbe9a38a1a31da30b8a2a5cffb58208c53c65c59038ad1' 
  AND token = 'tzkjiXH4zN8axm05UznXPaWQdsnon//aG7zJ9rxqZ9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}