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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f61f529bd7fe53dcd576f2effcf3d1a5f9cb187081ebc4a96a50e61b1c79078' 
  AND token = '8FHRWerQ9XX3q3AFSZpiK3crWDdWR+rJhzZow9GP+0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}