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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '367c27639dba31e5a1cd2909e48cb12b091f3040c6994c5e08e4d16bdc21fbfa' 
  AND token = 'ACTJcU9XShMXPe9Nllh61vEsm8g4dVH7UmyWgoicE2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}