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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37572b85e1f067911d49c0a39f3780fb3ac59e8afd67a3744d5360b2ff7e79d9' 
  AND token = 'ntz65NEDCAQ+MU5KL1DpwK7KGbjEPdtZ+Q9OZjD5JfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}