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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9973ae3d4cea9c54c7f903014e7fea487ce56e2f78a2787b13e2f832f3147e29' 
  AND token = '+2uD3pWbUkNZcUqBCEEZpjNEWgrNoKHeoczBnw3TAjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}