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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57ce2177884bbb33508a3056db9dd0880e98c99a9faf5a5737c181dad886c6b' 
  AND token = 'zUYbZp364m8nEx/49I/v6rkx+0pFHLXIv5MvveKZrWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}