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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a66d5f6217eb188b041259c5851042483c3022d53da31bde013d677c6bcb6a2' 
  AND token = 'GcUSAQvTbapfBDUgeJcgl6l+XTZxPAO/T/xuCiKasn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}