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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b8853216b4188cae1843a49900d2bafaa912d830318f7a37ade0d713e164ef9' 
  AND token = '8zJL5s3dWk5XSfZgnuEv84ZgTxPyxw2JAJ+ZQU9IfXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}