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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1235c57b853e8c2a7606a8b3c70079f631f0e3423e65e5781f6de6157656797' 
  AND token = '1ChUDxnphqBnslWiS05L7GhR3q9VcxyRJvlqK4qq9VQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}