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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5436ff541ae446cc4e6741a0a96f2299c1b7435001fc0d2667bf34a434f1e076' 
  AND token = 'w0eYgYiW+3n66NnKwEe7tCtKVwk9ecgKln7miZbujaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}