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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b5aa5c95c2d309a60df38fd8f135ad781dbcf936f07e75d32a8ce838b1e5fe9' 
  AND token = '5db3CZjEK8Urgh5LpAzga6S6W1Dic0Ax1HpH7sxwbTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}