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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6433c65a5bd96c1c556e9a0dc9fb21e8cb26e78608bb2c2500f9372c1aa37da' 
  AND token = '5O9EQYhYi3kA8a7+wzTLXTfnPgvxEJRfdgo+D+7loxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}