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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a804b31e2534dc951a8956a9508e609698dd67166f0a387ae2c40981e3346a0' 
  AND token = '+EsTOVdK7ZjKA6qd50mOrVC6680jjaEj+uopKKF7fNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}