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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f6858de4f59e88b8c56549cc73fd6e16e19ddc8af23e8410f1669f5b8125f3c' 
  AND token = 'XJjw1R5o5gfCp5hwtf0WhPpY+Ok1jv6wIDjJE6LvuB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}