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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12256c07f9cd8afa43f387de0a15e52d1fa45d5ed494581f09341096bd5f87a' 
  AND token = 'dmR2S/t2fe1lIsZEN/Y+X+FTjofXhGM53MURwaIUcCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}