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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8d6e145a9fbcd4cf95adea846638d64cff4d2229231ad3857e1b077042cbdf' 
  AND token = 'Vu+AbgxHJcSc7IVV1uXZws4uJPbd1T4P1snS89Ym5fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}