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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16ac1c5350b5d3eb0057606b99ad222930b8b6126e90e31d0e5d640aa2a9d81' 
  AND token = 'iyQpr76pwiGYsnhBGIV9Rh0844dqrRvZ80eoNytA4is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}