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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8211568c5b21de3879159f94c86da6cc6269a7e9387e40e39ffa19a49a95388a' 
  AND token = 'J4dB7zWmsinfimaaBIC942bhTvr7CECks6rhCz0tZ1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}