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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2fd9ad4f8f85b2a219e7ec1910714a1836338edc707fc3058a834c3c251842' 
  AND token = 'kRkDLkYKiWDtAe+yWMwPH/6aPhQZ0ATQ2HEU03ixNOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}