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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f53f98245d656af3d253f96e1a4decd52682c1302191c677c80e1194e51619' 
  AND token = 'Zrn0JBAFUYxFR6CSTPUqqj5ASvVPF+4WJ1c8UO17H7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}