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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd0c4c51f635f07449029370d37a282efaba18c3967bf9faf7bebdb8121bcd5' 
  AND token = 'qIHpvU/eDtjDTlqyseNnE0I2nC2W1VUAFwIeFJBtg+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}