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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '257a9364ba3ee9b2bb4cb0fc4e7c325f339ff8da49131548af326c0a9938d58d' 
  AND token = 'lCQr8YieBv1wNMC9mb5DDJVL3RwchWA1PnpFAXmKik0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}