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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c2ae5b588c2f0071e243cc4bb0709ab25fee769b4bc6528f782e8f7e1d30906' 
  AND token = 'F+EUEfYV3xZ00/o/WZJdvGS1yyj/8LJ7te+gOwT61uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}