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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea93050021e3f66631b6d18825a76151331557fc286ee6e3c5bc6a5a96127ffc' 
  AND token = 'i4KUzO1sa3hm3PKHW8uoKq2pkPZoonq+5brY6s7N5rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}