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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1643a4fef53536d5f02cdd5b16e139835287c74ea0425ebcaf634c9ec99b3919' 
  AND token = 'VLXzq+BkrLGhLiRkoQBP5UWdQ4upXVAHlRaLk5ROUZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}