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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f5affdc910aa704d4fef99106775b5447ddcb9da5af5df83bad39b6fba6db1' 
  AND token = 'TD0SCFpmab3KW0mI1aTs8+jEDT+8TMoNPgbpRff/xSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}