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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14cbff89634d09e1107dcceec2d952329e482a781e3657698c5e4f4e18cc0641' 
  AND token = 'XBeiqDc7aIXttUtcX4zKymORg+XveY73bhnk53Vk5o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}