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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '070cc660ecc908f8bbc800ba7489c306678594a40d9aef4be23ed1b87e154a74' 
  AND token = 'UexpbuzOVy8DTVYSbb3Y//V2HT1fMQrLo+eYChJYXGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}