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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ef6ce11e6b98c24b49c4992c680be6ff8bf214a5c6c892161cf453397f051d' 
  AND token = 'RKLrckXKZ+lpzPXW980UNe4h+lwNiCaJHLVZwVP1Xkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}