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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cefd9801594dc46ff379a674c188fade2b3df73e78dd2b9ff58f6b0698ae7448' 
  AND token = '4pSmSyPg6rGzA/pzGoLQ4Q+nghgr2tc9lPf/tEKTRH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}