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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e8cb54e8a3c4bfd5705c15ceb1f2245951aab4daaa316d465da6cf11e3b6292' 
  AND token = 'S21XwrP3aT01znI7vHb9zu1P4czGHYh6Nz5pIec3iK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}