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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2cfbdb95212b4b3f28ec7741e39dd38abd55d71a1d96ebbfdf5c30b90200a65' 
  AND token = '6V9ZHZVaTDNFBavIMtUVXEyPtShL7VbF+ndTwU92GEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}